Designers of anti-obesity drugs have suffered three major setbacks, but the potential reward from treating the world's fat epidemic is so great that their quest is unlikely to be deterred.

An unidentified woman takes a walk in Washington,DC in 2007. Designers of anti-obesity drugs have suffered three major setbacks, but the potential reward from treating the world's fat epidemic is so great that their quest is unlikely to be deterred.

Over-the-counter weight-loss pills are no quick fix to melt away extra pounds. Many local drugstores sell diet pills, and even more choices are available on the Internet. But most diet pills haven't been proved safe or effective, and some are downright dangerous, according to a special report in the November issue of Mayo Clinic Women's HealthSource.

Over-the-counter weight-loss pills are no quick fix to melt away extra pounds.

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